Yohimbe, a complex mixture, has been studied much less thoroughly than yohimbine, the pure compound.  Pharmaceutical grade yohimbine is usually presented as hydrochloride,:3, 14,34 which is more soluble. Subsequent work on yohimbine, which confirmed that it behaves as an aphrodisiac in animals, including rats, dogs, and golden hamsters, did not do so in humans. According to Betz: The son of a former New South Wales police officer told authorities he had “no idea” the supplements he ordered from the U.S. contained ingredients that could be illegally imported into Australia. If you suffer from erectile dysfunction, chances are you`re getting a lot of benefits from a natural testosterone booster. Many men don`t know that their testosterone levels start to drop in their early twenties and that this can cause problems. A testosterone booster can stimulate the body to maximize its own testosterone production and increase levels to their natural peak. Testosterone boosters are safe, legal and hormone-free.
A number of secondary reference works cite “quebrachin” as a synonym for yohimbine.          Despite its long-standing use, the supplement cannot be purchased in Australia due to its limited legal status. Buying yohimbine online and shipping it to Australia can also result in your package being confiscated at the border. The Australian government has issued a strong warning about a fake version of a dietary supplement containing yohimbine, claiming to increase “semen volume and intensity”. M. Katsogiannis said he had “no knowledge” that the product or ingredient DHEA was illegal in Australia and assumed there would be no problem if cleared through customs. He said he knew DMAA wasn`t licensed in Australia, but since Stim Lord`s container didn`t list it as an ingredient, “as far as I`m concerned, no DMAA, so I`m pretty good at walking.” Overall, the missing information includes quantitative data on the composition and specifications of yohimbe bark and its preparations used in foods and food supplements covering alkaloids other than yohimbine, data on the bioavailability of the active substances of yohimbe bark extract and data on the toxicity of well-specified individual preparations of yohimbe bark and the major alkaloids of yohimbe bark. Yohimbe bark. in particular with regard to subchronic toxicity, genotoxicity and reproductive toxicity. Yohimbine is known as an alpha-2 antagonist, which means it blocks alpha-2 receptors.
Alpha-2 receptors inhibit the release of catecholamine hormones such as adrenaline and norepinephrine, so blocking these receptors means higher levels of these stimulating hormones. Not only does it provide a feeling of energy, but blocking alpha-2 adrenergic receptors has been shown to improve thermogenesis and fat breakdown (1). Unlike many other supplements, yohimbine has been tested on humans and has been shown to have a reproducible and significant effect on reducing body fat (2,3,4). According to a TGA press release, the fake version of Semenax contains yohimbine, a compound made from the bark of the African yohimbe tree, and is completely banned in several countries (the real Semanax does not appear to contain yohimbine). Yohimbine is an alpha-blocker or medication that dilates blood vessels. In the United States, “yohimbe” supplements are sold as dietary supplements to increase libido, lose weight, and as a bodybuilding aid. But “there is virtually no published research on Yohimbe that supports these or other claims.” :861 Often these products explicitly claim to contain yohimbine.  (1) Lafontan M, Berlan M, Galitzky J, Montastruc JL. Alpha-2 adrenergics in lipolysis: alpha-2 antagonists and lipid mobilization strategies. At J Clin Nutr.
1992 Jan;55(1 Suppl):219S-227S. (2) Ostojic SM. Yohimbine: the effects on body composition and training performance in football players. 2006 Oct-Dec;14(4):289-99. (3) Galitzky J, Taouis M, Berlan M, River D, Garrigues M, Lafontan M. Alpha-2-antagonist compounds and lipid mobilization: evidence of a lipid mobilization effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988 Dec;18(6):587-94. (4) Berlan M, Galitzky J, Riviere D, Foureau M, Tran MA, Flores R, Louvet JP, Houin G, Lafontan M. Plasma catecholamine levels and yohimbine-induced lipid mobilization in obese and non-obese women.
Int J Obes. 1991 May;15(5):305-15. (5) McCarty MF. Administering yohimbine before exercise can improve exercise effectiveness as a fat loss strategy by increasing lipolysis. Hypotheses Med. 2002 Jun;58(6):491-5. (6) Ernst E, Pittler MH. Yohimbine for Erectile Dysfunction: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
J Urol. 1998 Feb;159(2):433-6. (7) Corazza O, Martinotti G, Santacroce R, Chillemi E, Di Giannantonio M, Schifano F, Cellek S. Sexual enhancement products for sale online: raising awareness of the psychoactive effects of yohimbine, maca, goat grass and Ginkgo biloba. 2014;2014:841798. (8) Ruck B, Shih RD, Marcus SM. Hypertensive crisis due to herbal treatment of impotence. Am J Emerg Med. 1999 May;17(3):317-8. Although there are no documented cases of legal action against consumers who purchase yohimbine supplements and bring them to Australia for personal use, this is still not recommended as your products may be confiscated by the authorities. Cohen et al.
found that samples of brands sold in U.S. brick and mortar stores contained very different amounts of yohimbine, and sometimes not at all. : 368 Labelling claims were often misleading. : 368 Similar results have been reported by other laboratories for products sold in the United States, other countries and on the Internet.      One study found that many brands of “yohimbe” may not even come down from the P. johimbe tree.  According to another source, yohimbe sold in West African markets where the tree grows is often adulterated with other species of the genus Pausinystalia; These contain little yohimbine.  The amounts of alkaloids even found in the true bark of P.
Johimbe vary considerably, depending on the source of the bark (roots, trunk, branches, height, etc.).  According to the Natural Medicines Database, yohimbine is considered potentially unsafe when used as a dietary supplement. However, it is considered safe if used under medical supervision for up to 10 weeks. The traditional source of yohimbine is the bark of the African tree P. johimbe. It has other uses, but the tree is sought after mainly for its bark; In practice, harvesting the bark kills the tree. The density of trees is relatively low (on average ≈ 4 usable trees/hectare). The high demand for bark-based medicines has led to overexploitation of the tree. The bark is traded in local markets and because it is rare, it is often adulterated with that of other species that contain little yohimbine.  The species is endangered.  Strictly speaking, George Barger wrote, yohimbine should have been given the scientific name quebrachin, since it was first isolated from the quebracho tree and first mentioned in the scientific literature. However, later work on P.
yohimbe was better known, so the new name stuck.  Research showing that yohimbine is ideal for pre-workout use and works synergistically with caffeine has made it an ideal ingredient in pre-workout and fat burner formulations (5). But that hasn`t stopped dozens of websites from aggressively marketing the pills. A quick search for “Semenax pills” brings up dozens of results and testimonials for the product, littered with promises to “increase your load” and give you “angry erections.” Pills marketed online are shipped just about everywhere, which is often illegal but difficult to control. Yohimbine comes from the bark of the Pausinystalia yohimbe tree, found in native forests in Central and West Africa, and is a plant alkaloid that inhibits presynaptic alpha-2-adrenergic receptors. He said he had seen the wording on the back of the supplements, “but I didn`t even consider it illegal” and “didn`t know it was a problem.” One of the main reasons yohimbine has been banned in Australia is the risk of adverse effects. Serious dangerous effects have occurred, especially when using high doses of this supplement. It has also been studied as a possible treatment for erectile dysfunction, but there is insufficient evidence to assess its effectiveness.    In the United States, it is illegal to market an over-the-counter product containing yohimbine for the treatment of erectile dysfunction without FDA approval.  Nevertheless, the amount of yohimbine in supplements, often advertised as promoting sexual function, has been found to overlap with prescription doses of yohimbine.
 People also use yohimbine to improve libido and counteract sexual dysfunction in both men and women caused by selective serotonin reuptake inhibitors (SSRIs) antidepressants.